20 March 2024
Rahul Varma
1. Recent studies in rodents suggest that restricting eating windows or mimicking fasting through diet may be linked to living a longer and healthier life.
2. The article explores a 5-day Fasting Mimicking Diet (FMD) that humans can implement.
3. FMD targets specific metabolites including IGF-1, IGFBP1, glucose, and ketone bodies.
4. The study measured biological age through a model that considers factors like liver and kidney function, blood pressure, and inflammation.
5. Fasting reduced abdominal and hepatic fat, lowered blood sugar levels in pre-diabetic individuals, and improved the immune profile in participants over 40.
6. After three cycles (months) of FMD, participants were found to be biologically 2.5 years younger than the control group.
7. Weight loss alone doesn't explain the positive effects of FMD on biological age.
8. The study suggests that FMD may add a few months to life expectancy, with the greatest gains for younger individuals.
9. The benefits of FMD were more pronounced for heart disease, stroke, and diabetes-related deaths compared to cancer.
10. While the study shows promise, more research is needed to confirm if changes in biological age translate to a longer lifespan.